High levels of chromosomal imbalances in typical and small-cell variants of T-cell prolymphocytic leukemia
✍ Scribed by Dolors Costa; Rosa Queralt; Marta Aymerich; Ana Carrió; Marı́a Rozman; Teresa Vallespı́; Dolors Colomer; Benet Nomdedeu; Emili Montserrat; Elı́as Campo
- Book ID
- 114135663
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 371 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0165-4608
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## Abstract T‐cell prolymphocytic leukemia (T‐PLL) is a rare malignant proliferation of lymphoid cells with a postthymic phenotype. Previous cytogenetic and molecular studies reported complex karyotypes with recurrent chromosomal abnormalities, including translocations involving either __TCL1__ at
Small cell carcinomas (SCCs) represent a rare histological subtype of urinary bladder cancer. Little is known abut the genetic alterations in these tumours. To identify chromosomal aberrations that are typically present in SCC of the urinary bladder, ten tumours were analysed by comparative genomic