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Short-chain fructooligosaccharides, in spite of being fermented in the upper part of the large intestine, have anti-inflammatory activity in the TNBS model of colitis

✍ Scribed by Federico Lara-Villoslada; Oscar de Haro; Desire Camuesco; Mónica Comalada; Javier Velasco; Antonio Zarzuelo; Jordi Xaus; Julio Galvez

Book ID
106066232
Publisher
Springer
Year
2006
Tongue
English
Weight
129 KB
Volume
45
Category
Article
ISSN
1436-6207

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UR-1505, a salicylate able to selectivel
UR-1505, a salicylate able to selectively block T-cell activation, shows intestinal anti-inflammatory activity in the chronic phase of the DSS model of rat colitis
✍ Elvira Bailón; Mònica Comalada; Juan Román; Pedro Michelena; Isabel Ramis; Manue 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB

Background: UR-1505 is a novel salicylate derivative compound that has been demonstrated to selectively down-regulate T-cell activation. The aim of the present study was to elucidate the mechanisms involved in the intestinal anti-inflammatory effects of UR-1505 in 2 protocols of a dextran sodium sul