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Intestinal anti-inflammatory activity of hydroalcoholic extracts of Phlomis purpurea L. and Phlomis lychnitis L. in the trinitrobenzenesulphonic acid model of rat colitis.

✍ Scribed by Algieri, Francesca; Zorrilla, Pedro; Rodriguez-Nogales, Alba; Garrido-Mesa, Natividad; Bañuelos, Óscar; González-Tejero, M. Reyes; Casares-Porcel, Manuel; Molero-Mesa, Joaquín; Zarzuelo, Antonio; Utrilla, M. Pilar; Rodriguez-Cabezas, M. Elena; Galvez, Julio

Book ID
121192063
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
999 KB
Volume
146
Category
Article
ISSN
0378-8741

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Background: UR-1505 is a novel salicylate derivative compound that has been demonstrated to selectively down-regulate T-cell activation. The aim of the present study was to elucidate the mechanisms involved in the intestinal anti-inflammatory effects of UR-1505 in 2 protocols of a dextran sodium sul