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Shock waves: a novel method for cytoplasmic delivery of antisense oligonucleotides

✍ Scribed by Katharina Tschoep; Gunther Hartmann; Ralf Jox; Steffi Thompson; Andreas Eigler; Anne Krug; Simon Erhardt; Gerhard Adams; Stefan Endres; Michael Delius

Book ID
105797572
Publisher
Springer
Year
2001
Tongue
English
Weight
178 KB
Volume
79
Category
Article
ISSN
0946-2716

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πŸ“œ SIMILAR VOLUMES

Thiolated polycarbophil as an adjuvant f
Thiolated polycarbophil as an adjuvant for permeation enhancement in nasal delivery of antisense oligonucleotides
✍ Vetter, A. (author);Martien, R. (author);Bernkop-SchnΓΌrch, A. (author) πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons Inc. 🌐 English βš– 281 KB

The purpose of this study was to investigate the effect of thiolated polycarbophil as an adjuvant to enhance the permeation and improve the stability of a phosphorothioate antisense oligonucleotide (PTO-ODN) on the nasal mucosa. Polycarbophil-cysteine (PCP-Cys) was synthesized by the covalent attach