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Severe uterus dysfunction in transgenic mice harboring a crosslinking mutation in type III collagen

✍ Scribed by Toman, D.; Starcher, B.; Mascara, T.; Robberson, D.; Smith, C.; Garrett, L.A.; Bateman, J.; de Crombrugghe, B.


Book ID
122896928
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
107 KB
Volume
14
Category
Article
ISSN
0945-053X

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Skeletal development of transgenic mice with a type II collagen mutation was analyzed and compared with wild-type littermates. The single base substitution in Col2a1 resulted in a glycine to serine mutation within the helical domain and corresponded to one previously identified in a patient with the