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Serum levels and genetic variation of TGF-β1 are not associated with Alzheimer’s disease

✍ Scribed by E. Rodríguez-Rodríguez; P. Sánchez-Juan; I. Mateo; J. Llorca; J. Infante; I. García-Gorostiaga; J. Berciano; O. Combarros

Book ID
109338662
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
123 KB
Volume
116
Category
Article
ISSN
0001-6314

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Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Aβ42 levels and risk for Alzheimer disease
✍ Nilüfer Ertekin-Taner; Mariet Allen; Daniel Fadale; Leah Scanlin; Linda Younkin; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB

## Communicated by Pui-Yan Kwok Risk for late onset Alzheimer disease (LOAD) and plasma amyloid beta levels (Ab42; encoded by APP), an intermediate phenotype for LOAD, show linkage to chromosome 10q. Several strong candidate genes (VR22, PLAU, IDE) lie within the 1-lod support interval for linkage