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Genetic variation in α1-antichymotrypsin and its association with Alzheimer’s disease

✍ Scribed by Xiaoyan Wang; Steven T. DeKosky; Erin Luedecking-Zimmer; Mary Ganguli; Ilyas M. Kamboh


Book ID
106133658
Publisher
Springer
Year
2002
Tongue
English
Weight
77 KB
Volume
110
Category
Article
ISSN
0340-6717

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We investigated a common signal peptide polymorphism in the ␣ 1-antichymotrypsin (ACT) gene in 125 sporadic Alzheimer disease (AD) patients and 141 healthy control subjects in Chinese Han population. We found no significant difference in the distribution of ACT polymorphism between AD cases and cont