## Abstract The amyloid β‐protein is a 39‐42 amino acid peptide that is deposited in senile plaques and in cerebral vessel walls in individuals with Alzheimer's disease, Down's syndrome, hereditary cerebral hemorrhage with amyloidosis–Dutch type (HCHW A‐D), and, to a much lesser extent, normal agin
✦ LIBER ✦
Decreased levels of soluble amyloid β-protein precursor are associated with Alzheimer's disease in concordant and discordant monozygous twin pairs
✍ Scribed by Dr. Steven L. Wagner; Elaine R. Peskind; David Nochlin; Sally Provow; Jeffrey S. Farrow; M. R. Pandian; Michelle Cleveland; Ralph K. Ito; Martin R. Farlow
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 705 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0364-5134
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## Abstract Alzheimer's disease (AD) is the most common form of dementia and is pathologically characterized by senile plaques, neurofibrillary tangles, synaptic disruption and loss, and progressive neuronal deficits. The exact mechanism(s) of AD pathogenesis largely remain unknown. With advances i