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Serum EGFR levels and efficacy of trastuzumab-based therapy in patients with metastatic breast cancer

✍ Scribed by Gernot Hudelist; Wolfgang J. Köstler; Daphne Gschwantler-Kaulich; Klaus Czerwenka; Ernst Kubista; Ruth Müller; Samir Helmy; Mahmood Manavi; Christoph C. Zielinski; Christian F. Singer


Book ID
116428742
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
178 KB
Volume
42
Category
Article
ISSN
0959-8049

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## Abstract Her‐2/__neu__ overexpression in human breast cancer leads to an aggressive biological behavior and poor prognosis. Although the anti‐Her‐2/__neu__ antibody trastuzumab (Herceptin®) has become a valuable therapeutic option for patients with Her‐2/__neu__‐overexpressing breast cancer, man