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Serological response to an HPV16 E7 based therapeutic vaccine in women with high-grade cervical dysplasia

✍ Scribed by Koenraad Van Doorslaer; Laura L. Reimers; Yevgeniy Y. Studentsov; Mark H. Einstein; Robert D. Burk


Book ID
113962109
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
371 KB
Volume
116
Category
Article
ISSN
0090-8258

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## Abstract Persistent infection with human papillomaviruses (HPV) is a prerequisite for the development of cervical cancer. Vaccination with virus‐like particles (VLP) has demonstrated efficacy in prophylaxis but lacks therapeutic potential. HPV16 L1E7 chimeric virus‐like particles (CVLP) consist