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OR.52. Phase I Evaluation of Therapeutic, E7-targeted DNA Vaccination in Women with HPV16+ High Grade Cervical Dysplasia (CIN2/3)

✍ Scribed by Cornelia Trimble; Shiwen Peng; Richard Roden; Patti Gravitt; Drew Pardoll; Elizabeth Sugar; Christopher Thoburn; Tzyy-Choou Wu

Book ID
113540202
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
37 KB
Volume
127
Category
Article
ISSN
1090-2341

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✍ Andreas M. Kaufmann; John D. Nieland; Ingrid Jochmus; Siegfried Baur; Klaus Frie 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 173 KB

## Abstract Persistent infection with human papillomaviruses (HPV) is a prerequisite for the development of cervical cancer. Vaccination with virus‐like particles (VLP) has demonstrated efficacy in prophylaxis but lacks therapeutic potential. HPV16 L1E7 chimeric virus‐like particles (CVLP) consist