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Sequential high-dose methotrexate, 5-fluorouracil, and doxorubicin for treatment of advanced pancreatic cancer

✍ Scribed by W. Scheithauer; J. Funovics; Ch. Mueller; H. Ludwig

Book ID
112574006
Publisher
Springer-Verlag
Year
1990
Tongue
English
Weight
216 KB
Volume
116
Category
Article
ISSN
1432-1335

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## Abstract Thirty patients with advanced measurable colorectal cancer were randomized to receive either methotrexate (MTX) 200 mg/m^2^ or 40 mg/m^2^, followed in four hours by 5‐fluorouracil (5‐FU) 600 mg/m^2^. Patients receiving the higher dose MTX were given leucovorin rescue 24 hours later. Eig