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Long-time infusion of sequential methotrexate and 5-fluorouracil in the treatment of advanced colorectal cancer

✍ Scribed by E. J. Borghardi; St. Döll; R. Fock; U. Plener

Book ID
112785596
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
131 KB
Volume
111
Category
Article
ISSN
1432-1335

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## Abstract Thirty patients with advanced measurable colorectal cancer were randomized to receive either methotrexate (MTX) 200 mg/m^2^ or 40 mg/m^2^, followed in four hours by 5‐fluorouracil (5‐FU) 600 mg/m^2^. Patients receiving the higher dose MTX were given leucovorin rescue 24 hours later. Eig