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Phase II study of sequential high-dose methotrexate and fluorouracil combined with doxorubicin as a neoadjuvant chemotherapy for scirrhous gastric cancer

✍ Scribed by Shinichiro Takahashi; Taira Kinoshita; Masaru Konishi; Toshio Nakagouri; Kazuto Inoue; Masato Ono; Masanori Sugitou; Atsushi Ohtsu; Narikazu Boku; Shigeaki Yoshida

Publisher: Springer
Year: 2001
Tongue: English
Weight: 73 KB
Volume: 4
Category: Article
ISSN: 1436-3291
DOI: 10.1007/s10120-001-8009-5

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## Background: Based on the promising results of eap (etoposide, doxorubicin, and cisplatin) combination, a phase ii study of modified eap combination was performed in patients with advanced gastric cancer to evaluate the response, toxicity, and survival. ## Method: Fifty-two consecutive patients