A phase II study of weekly high-dose 5-fluorouracil and leucovorin plus biweekly alternating doxorubicin and cisplatin for advanced gastric carcinoma
✍ Scribed by M. Raida; R. Kath; M. Arnrich; G. Kähler; J. Scheele; K. Höffken
- Publisher
- Springer-Verlag
- Year
- 1998
- Tongue
- English
- Weight
- 277 KB
- Volume
- 124
- Category
- Article
- ISSN
- 1432-1335
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📜 SIMILAR VOLUMES
To determine the feasibility and toxicity of combining leucovorin (CF) with a 5fluorouracil(5-FU) combination chemotherapy regimen currently accepted by many as standard treatment for gastric cancer, CF (500 mg/m') was administered in combination with the Georgetown S-FU, doxorubicin, and mitomycin
Background. In a previous Phase I1 trial, the authors showed that a weekly continuous infusion of 5-fluorouracil (5-FU) at a dose of 3.5 g/mz for 48 hours is an active treatment for advanced colorectal cancer. The overall response rate was 38.5%, and the median survival was 12 months. These data wer