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Sequential assays of hormone receptors and the tritiated thymidine labeling index in 7,12-dimethylbenz(a)anthracene-induced rat mammary cancers

โœ Scribed by Keisuke Araki; Masaharu Kimura; Kiyoshi Sakamoto; Reiki Nishimura; Junichi Yamashita; Masanobu Akagi


Book ID
112755415
Publisher
Springer
Year
1985
Tongue
English
Weight
571 KB
Volume
15
Category
Article
ISSN
1436-2813

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โœ Gordon H. Sasaki; Dr. Benjamin S. Leung ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 552 KB

The presence of ER in DMBA-tumors was demonstrated by the use of dextrancharcoal assay, sephadex chromatography, sucrose gradient sedimentation, and organ culture techniques. It was found that tumors have binding sites ranging from 10-" to 10-l' moles/mg protein, and a dissociation constant of ER 10