The positive-and negative-ion collision-induced dissociation spectra of peptides containing methionine, methionine sulphoxide and methionine sulphone have been studied. Characteristic fragmentations were identified and evaluated as possible indicators for the presence of oxidized methionine residues
Sequencing of oxidized methionine-containing peptides for protein identification
β Scribed by Wenjun Mo; Yuliang Ma; Toshifumi Takao; Thomas A. Neubert
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 41 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0951-4198
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Treatment of peptides containing methionine and/or tryptophan with dimethylsuifoxide/hydrochloric acidlacetic acid resulted in oxidation of these amino acids respectively to methionine sulfoxide and oxyindolalanine. This reaction was monitored by fast atom bombardment mass spectrometry using a dithi
We describe the construction of a compact protein sequencer designed specifically for the C-terminal sequence analysis of peptides and proteins. This sequencer has a vertical flow path and is equipped with a continuous flow reactor (CFR). The flow paths for the various reagents and solvents have bee