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Sequences and topology: intrinsic disorder in the evolving universe of protein structure

โœ Scribed by A Keith Dunker; Julian Gough


Book ID
113883431
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
382 KB
Volume
21
Category
Article
ISSN
0959-440X

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The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin -dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. The 26S proteasome is made of two co