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A Comparative Study of the Relationship Between Protein Structure and β-Aggregation in Globular and Intrinsically Disordered Proteins

✍ Scribed by Rune Linding; Joost Schymkowitz; Frederic Rousseau; Francesca Diella; Luis Serrano

Book ID
116661469
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
245 KB
Volume
342
Category
Article
ISSN
0022-2836

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The degradation of the majority of cellular proteins is mediated by the proteasomes. Ubiquitin -dependent proteasomal protein degradation is executed by a number of enzymes that interact to modify the substrates prior to their engagement with the 26S proteasomes. The 26S proteasome is made of two co