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Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy

✍ Scribed by Donfack, Joseph; Kogut, Paul; Forsythe, Sean; Solway, Julian; Ober, Carole

Book ID: 122921580
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 101 KB
Volume: 111
Category: Article
ISSN: 1097-6825
DOI: 10.1067/mai.2003.71

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## Abstract Pathological deregulation of the transforming growth factor, beta 1 (TGFB1) pathway has been implicated in the development of several major diseases, including cancers. Regulatory variation in the __TGFB1__ gene may lead to altered __TGFB1__ expression and activity, and thus, modulate a