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DNA sequence variation in the promoter region of the VEGF gene impacts VEGF gene expression and maximal oxygen consumption

✍ Scribed by Prior, S. J.


Book ID
125494564
Publisher
The American Physiological Society
Year
2006
Tongue
English
Weight
129 KB
Volume
290
Category
Article
ISSN
0363-6135

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## Abstract Promoter‐region DNA methylation inhibits transcription. A two‐stage SENCAR (__sen__sitive to mouse __car__cinogenesis) mouse skin carcinogenicity model was used to examine gene‐specific changes in methylation during skin tumor promotion. Analysis was performed on 7,12‐dimethylbenz[a]ant