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Sequence of centromere separation of mitotic chromosomes in Chinese hamster

โœ Scribed by Baldev K. Vig; Herbert G. Miltenburger


Publisher
Springer
Year
1976
Tongue
English
Weight
662 KB
Volume
55
Category
Article
ISSN
0009-5915

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โœฆ Synopsis


Chromosome preparation in late metaphase cells from bone marrow of colcemid treated male Chinese hamsters were used to analyse the sequence of separation of sister centromeres. Chromatids of chromosomes 2 and 1 are the first ones to separate at centromeres, followed by members of group B, D and C. Some acrocentric chromosome is always the last one to separate at the centromere. The data point to a possible correlation between the position of a centromere in the separation sequence in the genome and the amount of centromeric heterochromatin as well as relation to the phenomenon of non-disjunction.


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