Sequence of centromere separation of mitotic chromosomes in Chinese hamster
โ Scribed by Baldev K. Vig; Herbert G. Miltenburger
- Publisher
- Springer
- Year
- 1976
- Tongue
- English
- Weight
- 662 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0009-5915
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โฆ Synopsis
Chromosome preparation in late metaphase cells from bone marrow of colcemid treated male Chinese hamsters were used to analyse the sequence of separation of sister centromeres. Chromatids of chromosomes 2 and 1 are the first ones to separate at centromeres, followed by members of group B, D and C. Some acrocentric chromosome is always the last one to separate at the centromere. The data point to a possible correlation between the position of a centromere in the separation sequence in the genome and the amount of centromeric heterochromatin as well as relation to the phenomenon of non-disjunction.
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