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The effect of cyclophosphamide on the centromere separation sequence in Chinese hamster spermatogonia

✍ Scribed by Jai Rup Singh; Herbert G. Miltenburger

Publisher
Springer
Year
1977
Tongue
English
Weight
224 KB
Volume
39
Category
Article
ISSN
0340-6717

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✦ Synopsis

The sequence of centromere separation in spermatogonial chromosomes of untreated and cyclophosphamide-treated Chinese hamsters is described. Centromeres of chromosome 1 and 2 separated much earlier than all other chromosomes, especially 6-8. Cyclophosphamide significantly inhibits the centromere separation in all chromosome groups but does not alter the sequence of separation.

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