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Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast

✍ Scribed by Allyson L Valente,Seth Rummel,Craig D Shriver…


Book ID
126380620
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
241 KB
Volume
12
Category
Article
ISSN
1897-4287

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## Communicated by Riccardo Fodde BRCA1 mutation detection is expensive and has sensitivity limitations, which might at least partially be overcome by RNA-based sequencing. There are claims that RNA tests are unreliable due to differential splicing, exon skipping, or nonsense-mediated mRNA decay t