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Contribution of germline MLH1 and MSH2 mutations to lobular carcinoma in situ of the breast

✍ Scribed by J.G Stone; G Coleman; B Gusterson; A Marossy; S.R Lakhani; A Ward; A Nash; A McKinna; R A'Hern; M.R Stratton; R.S Houlston

Book ID: 117466886
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 71 KB
Volume: 167
Category: Article
ISSN: 0304-3835
DOI: 10.1016/s0304-3835(01)00448-7

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Lobular carcinoma in situ (LCIS) of the breast is commonly identified as an incidental finding in breast biopsies performed because of either a mammographic abnormality or a palpable mass. Although long recognized as an entity, the significance and optimal treatment of LCIS remains controversial. In