Sepsis and Organ Dysfunction: Epidemiology and Scoring Systems Pathophysiology and Therapy

✍ Scribed by L. Ilkka, J. Takala (auth.), A. E. Baue M.D., G. Berlot M.D., A. Gullo M.D. (eds.)

Publisher: Springer-Verlag Mailand
Year: 1998
Tongue: English
Leaves: 177
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Sepsis is a syndrome or sometimes it is a clinical condition evoked by uncontrolled endotoxin-reactions. These pathophysiological alterations can disturb the organism's homeostasis leading ultimately to a condition of severe organ dysfunction which in itself means a bad prognosis for patient survival. In the last decades researchers and clinicians have been involved in process directed to a better understanding of the basic mechanisms of sepsis and MODS. The best goal will be the achievement of preventive measures and optimization of management in patients suffering severe infections and critical conditions. This objective represents a true challenge at the dawn of the XXI century.

✦ Table of Contents

Front Matter....Pages I-XII
Front Matter....Pages 13-13
Epidemiology and Clinical Course of Sepsis....Pages 15-21
The Complexities of Sepsis and Organ Dysfunction....Pages 23-31
Front Matter....Pages 33-33
An Overview to Introduce Prognostic Indexes in MODS....Pages 35-44
Multiple Organ Dysfunction (MOD) Score....Pages 45-51
The Logistic Organ Dysfunction (LOD) System....Pages 53-64
Will the Use of Scores Benefit the Individual Patient and Improve Therapy?....Pages 65-69
Front Matter....Pages 71-71
Old and New Mediators in Sepsis The Enigma Is Not Yet Resolved....Pages 73-80
Modulating Prostaglandin Metabolism in Sepsis....Pages 81-88
Front Matter....Pages 89-89
Oxygen Delivery and Consumption Relationships in Sepsis — The Role of Inotropic and Vasoactive Drugs....Pages 91-96
Front Matter....Pages 97-97
Disturbances and Modulators of Coagulation and Fibrinolysis in Sepsis....Pages 99-111
Front Matter....Pages 113-113
Therapies Directed against TNF-α and IL-1 during Sepsis....Pages 115-121
Effects of Adrenergic Agents on the Hepato-Splanchnic Circulation: An Update....Pages 123-130
When to Operate or to Stop Operating and to Plan a Reoperation....Pages 131-144
Multiple Therapeutic Agents — Are We Making Progress?....Pages 145-152
Front Matter....Pages 153-153
SIRS and Sepsis-Induced Neuromuscular Dysfunctions....Pages 155-164
Front Matter....Pages 165-165
Lights and Shadows in Sepsis and Multiple Organ Dysfunction Syndrome (MODS)....Pages 167-188
Back Matter....Pages 189-192

✦ Subjects

Medicine/Public Health, general

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