A micellar electrokinetic capillary chromatographic method for the separation of tetrahydroberberine alkaloids was established. An electrolyte solution of 0.02 M sodium dodecyl sulphate (SDS) in 0.03 M borate buffer (pH 9) containing 10% acetonitrile, and an applied voltage of 20 kV, were found to b
Separation of doxorubicin and doxorubicinol by cyclodextrin-modified micellar electrokinetic capillary chromatography
β Scribed by Angela R. Eder; Jennifer S. Chen; Edgar A. Arriaga
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 265 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0173-0835
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The enantiomeric separation of atropisomeric polychlorinated biphenyls Ε½ was studied by cyclodextrin-modified micellar electrokinetic chromatography CD-. MEKC . Four CD derivatives were investigated as chiral selectors, and 2-hydroxyl-β₯-CD gave the best resolution for the separation of PCB 84. Three
## Abstract A simple method for the separation of highly hydrophobic neutral enantiomers by cyclodextrinβmodified micellar electrokinetic chroβmatography (MEKC) is presented and strongly supported by experiments. The separation depends on the ratio between the concentrations of cyclodextrin (CD) an