## Abstract Twentyβtwo sulphonamides and three dihydrofolate reductase inhibitors (DHFR) were included in this study. At pH 7.5, eighteen drugs were resolved in 22 min. Above pH 7.5 the DHFR are not resolved and the pH range of 7β7.5 was found to be optimal. Around pH 7, where the degree of ionizat
Separation of Dihydrofolate Reductase Inhibitors by RP-HPLC and Comparison with Capillary Zone Electrophoresis
β Scribed by Cross, R. F. ;Cao, J. ;Tilling, A.
- Publisher
- Springer-Verlag
- Year
- 2004
- Weight
- 83 KB
- Volume
- 149
- Category
- Article
- ISSN
- 0344-838X
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