Separation and Thermal Racemization of the Enantiomers of Spiro[cyclohexadiene-dihydroacridines]
β Scribed by Thomas Zimmermann; Nikola Pustet; Albrecht Mannschreck
- Book ID
- 106214832
- Publisher
- Springer Vienna
- Year
- 2000
- Tongue
- English
- Weight
- 122 KB
- Volume
- 131
- Category
- Article
- ISSN
- 0026-9247
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Chiral spirobinaphtopyrans 1-9 were synthesised using the acid catalyzed aldol condensation of 2-hydroxy-1-naphthaldehyde or 1-hydroxy-2-naphthaldehyde with the appropriate ketone and subsequent reaction of the isolated pyrylium salt with base. Separation or enrichment of enantiomers was accomplishe
The separation of the enantiomers of 7aH-cyclopenta[b]pyran-7-ones 1 was performed by enantioselective liquid chromatography with the sorbent/solvent systems triacetylcellulose/methanol, tribenzoylcellulose/methanol, and (+)-poly(trityl methacrylate)/silica gel/n-heptane/isopropanol.