๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The enantiomers of 7aH-cyclopenta[b]pyran-7-ones and their thermal racemization

โœ Scribed by Thomas Zimmermann; Nikola Pustet; Albrecht Mannschreck

Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
37 KB
Volume
341
Category
Article
ISSN
1615-4150

No coin nor oath required. For personal study only.

โœฆ Synopsis

The separation of the enantiomers of 7aH-cyclopenta[b]pyran-7-ones 1 was performed by enantioselective liquid chromatography with the sorbent/solvent systems triacetylcellulose/methanol, tribenzoylcellulose/methanol, and (+)-poly(trityl methacrylate)/silica gel/n-heptane/isopropanol.

๐Ÿ“œ SIMILAR VOLUMES

Study of the kinetic resolution of (ยฑ)-1
Study of the kinetic resolution of (ยฑ)-10-exo-hydroxy-pentacyclo[6.2.1.13,6.02,7.05,9]dodeca-4-one by lipase catalysis and the intramolecular racemization of the pure enantiomer by thermal dyotropic reaction
โœ Josรฉ E.D. Martins; Joรฃo Alifantes; Adriana R. Pohlmann; Valentim E.U. Costa ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 226 KB

In this work, the modified synthesis of (ยฑ)-10-exo-hydroxy-pentacyclo[6.2.1.1 3,6 .0 2,7 .0 5,9 ]dodeca-4-one (ยฑ)-10 as well as its resolution by lipase-catalyzed transesterification with vinyl acetate is described. A thermal racemization process of (+)-10 to (ยฑ)-10 was observed. A mechanism involvi