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Sensitivity of Bald Eagle (Haliaeetus leucocephalus) Hepatocyte Cultures to Induction of Cytochrome P4501A by 2,3,7,8-Tetrachlorodibenzo-p-dioxin

✍ Scribed by Sean W. Kennedy; Stephanie P. Jones; John E. Elliott


Book ID
110421653
Publisher
Springer
Year
2003
Tongue
English
Weight
175 KB
Volume
12
Category
Article
ISSN
0963-9292

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Oral doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were administered twice within 7 d (total concentration 0.01, 0.1, 1, 10, or 100 g TCDD/kg body weight) to flounder (Platichthys flesus). After 10 d of exposure, flounder were sacrificed, and the effects of TCDD exposure on hepatic microsomal