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2,3,4,7,8-pentachlorodibenzofuran is a more potent cytochrome P4501A inducer than 2,3,7,8-tetrachlorodibenzo-p-dioxin in herring gull hepatocyte cultures

✍ Scribed by Jessica C. Hervé; Doug L.D. Crump; Kristina K. McLaren; John P. Giesy; Matthew J. Zwiernik; Steven J. Bursian; Sean W. Kennedy

Book ID
102194352
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
176 KB
Volume
29
Category
Article
ISSN
0730-7268

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High induction of cytochrome p4501a acti
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✍ H. T. Besselink; E. van Santen; W. Vorstman; A. D. Vethaak; J. H. Koeman; A. Bro 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB

Oral doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) were administered twice within 7 d (total concentration 0.01, 0.1, 1, 10, or 100 g TCDD/kg body weight) to flounder (Platichthys flesus). After 10 d of exposure, flounder were sacrificed, and the effects of TCDD exposure on hepatic microsomal