A microcantilever sensor was developed to detect lysozyme in a pharmaceutical formulation based on the principle of atomic force microscopy. By measuring the cantilever bending and deflection using the optical reflection technique, the lysozyme adsorption on a dodecanethiol-modified cantilever surfa
Sensitivity improvement of a microcantilever based mass sensor
✍ Scribed by Margarita Narducci; Eduard Figueras; María José Lopez; Isabel Gràcia; Joaquin Santander; Peter Ivanov; Luis Fonseca; Carles Cané
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 347 KB
- Volume
- 86
- Category
- Article
- ISSN
- 0167-9317
No coin nor oath required. For personal study only.
✦ Synopsis
This article describes two approaches for sensitivity improvement of a micromachined silicon T-shaped cantilever resonator for mass sensing applications. In order to increase sensitivity values, higher order resonance mode was used and device dimensions were reduced. The cantilevers proposed are piezoelectrically actuated and the movement detection is done by four piezoresistors in a Wheatstone bridge configuration. Two types of cantilevers were fabricated: for the first cantilever of 400 lm long, 300 lm wide and 15 lm thick, the fundamental and second resonance frequency in air were 100 kHz ± 0.4 and 690 kHz ± 15, respectively, both with a quality factor of $800. And for the second cantilever of 200 lm long, 150 lm wide, 15 lm thick, the fundamental resonance frequency in air was 400 kHz ± 5 with a quality factor of $900. The devices were characterized attaching microspheres of polystyrene to the cantilever's surface tip and measuring resonance frequency changes. For the first cantilever sensitivity values of 0.07 and 0.3 Hz/pg for the fundamental and second mode, respectively were achieved and 1.3 Hz/pg for the second cantilever. These results show the great potential for high sensitive mass sensor of this simple device.
📜 SIMILAR VOLUMES
## Abstract We present a feasibility study of ZnO‐based FBAR devices and their fabrications for the ultra‐mass‐sensitive sensor application. In this work, a considerable shift in the resonance frequency is observed due to the mass‐loading effect by a mixture of ink and volatile methanol. A high sen