Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis
โ Scribed by M Van Gele; N Van Roy; A Jauch; G Laureys; Y Benoit; V Schelfhout; C.R De Potter; P Brock; A Uyttebroeck; R Sciot; E Schuuring; R Versteeg; F Speleman
- Book ID
- 117663997
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 149 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0959-8049
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Comparative genomic hybridization (CGH) was recently developed as a tool to survey entire genomes for variations in DNA sequence copy numbers. We have applied this technique to detect and map amplified regions in 54 soft tissue sarcomas. Aberrations were detected by visual analysis of hybridization