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Sensing of energy and nutrients by AMP-activated protein kinase

✍ Scribed by Hardie, D. G.


Book ID
124150436
Publisher
American Society for Clinical Nutrition:
Year
2011
Tongue
English
Weight
140 KB
Volume
93
Category
Article
ISSN
0002-9165

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AMP-activated protein kinase: the energy
✍ D. Grahame Hardie; Simon A. Hawley πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 142 KB

## Abstract The AMP‐activated protein kinase cascade is a sensor of cellular energy charge, and its existence provides strong support for the energy charge hypothesis first proposed by Daniel Atkinson in the 1960s. The system is activated in an ultrasensitive manner by cellular stresses that deplet