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Senescence: back to telomeres

✍ Scribed by Jacobs, Jacqueline J. L.

Book ID
120077329
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
102 KB
Volume
14
Category
Article
ISSN
1471-0072

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Eukaryotic chromosomes end with tandem repeats of simple sequences. These GC rich repeats allow telomere replication and stabilize chromosome ends. Telomere replication involves an equilibrium of sequence loss and addition at the ends of chromosomes. Repeats are added de now by telomerase, an unusua