Telomeres, telomerase and senescence
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Carol W. Greider
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Article
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1990
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John Wiley and Sons
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English
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Eukaryotic chromosomes end with tandem repeats of simple sequences. These GC rich repeats allow telomere replication and stabilize chromosome ends. Telomere replication involves an equilibrium of sequence loss and addition at the ends of chromosomes. Repeats are added de now by telomerase, an unusua