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Semipreparative enantioseparation of Tröger base derivatives by HPLC

✍ Scribed by Sergey Sergeyev; François Diederich


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
210 KB
Volume
18
Category
Article
ISSN
0899-0042

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Enantioseparation of tiropramide by HPLC
✍ Jae Jeong Ryoo; Kyu Sung Heo; Eun-Soon Choi; Jung Hag Park; Wonjae Lee 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 310 KB

Tiropramide is an antispasmodic drug that has a chiral center. Resolution of tiropramide enantiomers on various kinds of chiral stationary phases was performed by HPLC. A good resolution on a leucine-derived chiral stationary phase was found. An improved chromatographic condition to resolve racemic