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Self-Promoted Aldol Reaction Between Aldehyde Having Lewis Base Moiety and Trimethylsilyl Enolate.

✍ Scribed by Takashi Nakagawa; Hidehiko Fujisawa; Teruaki Mukaiyama


Publisher
John Wiley and Sons
Year
2004
Weight
158 KB
Volume
35
Category
Article
ISSN
0931-7597

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Product-Catalyzed Aldol Reaction between
✍ Hidehiko Fujisawa; Takashi Nakagawa; Teruaki Mukaiyama πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 240 KB πŸ‘ 1 views

## Abstract Aldol reactions between trimethylsilyl ketene acetals and aldehydes by using a catalytic amount of alkoxide anion proceeded smoothly to afford the corresponding aldols in DMF, indicating that the initially‐formed aldolate anion effectively worked to catalyze the reaction. The β€œproduct‐c