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Self-assembly, DNA Complexation, and pH Response of Amphiphilic Dendrimers for Gene Transfection

✍ Scribed by Guillot-Nieckowski, Marine; Joester, Derk; Stöhr, Meike; Losson, Myriam; Adrian, Marc; Wagner, Bjoern; Kansy, Manfred; Heinzelmann, Harry; Pugin, Raphaël; Diederich, François; Gallani, Jean-Louis


Book ID
127395441
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
801 KB
Volume
23
Category
Article
ISSN
0743-7463

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Synthesis of Pyridinium Amphiphiles Used
✍ Arthur A. P. Meekel; Anno Wagenaar; Jarmila Šmisterová; Jessica E. Kroeze; Peter 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 778 KB

Pyridinium amphiphiles have found practical use for the delivery of DNA into cells. Starting from 4-methylpyridine, a general synthesis has been devised for the production of pyridinium amphiphiles which allows variation in both the hydrophobic part and in the headgroup area of the compounds.