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Self-assembled filamentous nanostructures for drug/gene delivery applications

โœ Scribed by Lee, Jun-hyung; Choi, Young Joo; Lim, Yong-beom

Book ID
120458378
Publisher
Informa plc
Year
2010
Tongue
English
Weight
609 KB
Volume
7
Category
Article
ISSN
1742-5247

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Self-assembled oligopeptide nanostructur
Self-assembled oligopeptide nanostructures for co-delivery of drug and gene with synergistic therapeutic effect
โœ Nikken Wiradharma; Yen Wah Tong; Yi-Yan Yang ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 720 KB

In this study, oligopeptide amphiphile containing three blocks of amino acids, Ac-(AF) 6 -H 5 -K 15 -NH 2 (FA32), were synthesized and evaluated as carriers for co-delivery of drug and gene. Doxorubicin (DOX), luciferase reporter gene, and p53 gene were used as a model drug and genes. The peptide am