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Physical hydrogels with self-assembled nanostructures as drug delivery systems

✍ Scribed by Tang, Yiqing; Heaysman, Clare L; Willis, Sean; Lewis, Andrew L

Book ID
117989712
Publisher
Informa plc
Year
2011
Tongue
English
Weight
713 KB
Volume
8
Category
Article
ISSN
1742-5247

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In this study, oligopeptide amphiphile containing three blocks of amino acids, Ac-(AF) 6 -H 5 -K 15 -NH 2 (FA32), were synthesized and evaluated as carriers for co-delivery of drug and gene. Doxorubicin (DOX), luciferase reporter gene, and p53 gene were used as a model drug and genes. The peptide am