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Selective reduction of carbonyl groups in the presence of low-valent titanium reagents

โœ Scribed by Lin, Wei; Hu, Ming-Hua; Feng, Xian; Fu, Lei; Cao, Cheng-Pao; Huang, Zhi-Bin; Shi, Da-Qing


Book ID
123051824
Publisher
Elsevier Science
Year
2014
Tongue
French
Weight
879 KB
Volume
55
Category
Article
ISSN
0040-4039

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Low valent titanium mediated cleavage of N-propargyl bonds offers a facile, mild, and high yielding method for the deprotection of amines under neutral conditions. The methodology could be used for the chemoselective removal of propargyl groups ~orn amines in preference to the allyl/henzyl counterpa