Selective recognition of pyrimidine motif triplexes by a protein encoded by the bacterial transposon Tn7
β Scribed by Jason E Rao; Nancy L Craig
- Book ID
- 115630939
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 415 KB
- Volume
- 307
- Category
- Article
- ISSN
- 0022-2836
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To develop a novel nucleoside analogue for the effective recognition of CG interruption in a homopurine -homopyrimidine tract of double-stranded DNA (dsDNA), we succeeded in the synthesis of a triplex-forming oligonucleotide (TFO) containing a novel 2 0 ,4 0 -BNA (Q B ) bearing 1-isoquinolone as a n
The ~t-nucleoside 7-(2'-deoxy-ct-D-ribofuranosyl)hypoxanthine, incorporated into an otherwise 13configured oligodeoxynucleotide that is designed to bind to a DNA duplex in the parallel motif, recognizes selectively and efficiently a G-C base pair, presumably via monodentate ct-H7oG-C base-triple for