In this study, electrospray ionization mass spectrometry (ESI-MS) is used to study the formation of G-quadruplex by d(GGAGGAGGAGGA) which locates at the promoter region of c-myb gene. In addition, a natural small molecule, dehydrocorydaline from a Chinese herb, is found to have the highest binding a
β¦ LIBER β¦
Selective recognition of oncogene promoter G-quadruplexes by Mg2+
β Scribed by Yi-Yong Yan; Jing Lin; Tian-Miao Ou; Jia-Heng Tan; Ding Li; Lian-Quan Gu; Zhi-Shu Huang
- Book ID
- 116300978
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 497 KB
- Volume
- 402
- Category
- Article
- ISSN
- 0006-291X
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## Abstract **NΓ€schen fΓΌr Proteine:** Aus fluoreszierenden DNAβGβQuadruplexen wurden vielseitige Signalrezeptoren fΓΌr Proteine in LΓΆsung aufgebaut. Die EinfΓΌhrung einer Proteinprobe in das Ensemble resultiert in einem einzigartigen, charakteristischen Emissionsmuster (siehe Schema, R = Fluorophor).