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Protein Recognition by an Ensemble of Fluorescent DNA G-Quadruplexes

✍ Scribed by David Margulies; Andrew D. Hamilton

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
549 KB
Volume
121
Category
Article
ISSN
0044-8249

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✦ Synopsis

Abstract

Näschen für Proteine: Aus fluoreszierenden DNA‐G‐Quadruplexen wurden vielseitige Signalrezeptoren für Proteine in Lösung aufgebaut. Die Einführung einer Proteinprobe in das Ensemble resultiert in einem einzigartigen, charakteristischen Emissionsmuster (siehe Schema, R = Fluorophor). Die selbstorganisierten Proteindetektionssysteme sind leicht herstellbar, für Hochdurchsatzverfahren geeignet und auf kleine Proteinproben anwendbar.magnified image

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