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Selective Oxidation of Sulfides to Sulfoxides with Cetyltrimethylammonium Periodate

โœ Scribed by Chaudhari, Umesh V.; Deota, Pradeep T.


Book ID
111966569
Publisher
Taylor and Francis Group
Year
2012
Tongue
English
Weight
146 KB
Volume
44
Category
Article
ISSN
0030-4948

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Synthesis of cetyltrimethylammonium trib
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The bright yellow crystalline cetyltrimethylammonium tribromide (CTMATB) reagent has been synthesized from the reaction of CTMAB and KBr with H 2 MoO 4 โ€ขH 2 O, H 2 O 2 and H 2 SO 4 in the molar ratio 1:2:0.01:4:0.93. CTMATB selectively oxidizes a variety of dialkyl and alkyl aryl sulfides to the cor

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Selective oxidation of sulfides to sulfoxides is achieved using H 2 O 2 and TMSCl as the promotor. Aromatic and aliphatic sulfides are oxidized to sulfoxides in excellent yields and in short reaction times. Different functional groups including ketone, alkene, ester, and alcohol are tolerated.

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