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Selective Inhibition of Growth of Transformed Cells by Protease Inhibitors

✍ Scribed by Hans Peter Schnebli and Max M. Burger


Book ID
123651347
Publisher
National Academy of Sciences
Year
1972
Tongue
English
Weight
540 KB
Volume
69
Category
Article
ISSN
0027-8424

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We investigated the effects of three serine protease inhibitors (leupeptin, soybean trypsin inhibitor, and aprotinin) on the serum-free growth of two transformed cell lines in soft agar. Aprotinin markedly enhanced the growth of rat embryo fibroblasts that had been transformed by polyoma middle T an