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Selective inhibition of translation in transformed cells

✍ Scribed by Luis Carrasco


Book ID
115910617
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
241 KB
Volume
110
Category
Article
ISSN
0014-5793

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Selective cytotoxicity of tunicamycin fo
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## Abstract We have studied the effects of tunicamycin, an inhibitor of dolichol pyrophosphate‐dependent glycosylation of proteins, on the viability of transformed and non‐transformed fibroblasts in culture. We have shown that a low concentration of tunicamycin (0.05 ΞΌg/ml or 5 Γ— 10^βˆ’8^ M) is cytot