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Non-Selective Inhibition of Transformed Cell Growth by a Protease Inhibitor

✍ Scribed by Iih-Nan Chou, Paul H. Black and Richard O. Roblin


Book ID
123652382
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
816 KB
Volume
71
Category
Article
ISSN
0027-8424

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We investigated the effects of three serine protease inhibitors (leupeptin, soybean trypsin inhibitor, and aprotinin) on the serum-free growth of two transformed cell lines in soft agar. Aprotinin markedly enhanced the growth of rat embryo fibroblasts that had been transformed by polyoma middle T an